Medical Marijuana

The Science Behind the EC System

The EC system is central to your well being and wellness. Right here’s how this self regulatory community works to maintain you balanced and how one can help it with CBD oil.

As you got down to be taught extra about cannabidiol (CBD) oil and the way it naturally promotes wellness, undoubtedly you’ll come throughout a reference to the EC system.

The EC system, or endocannabinoid system, is the rationale CBD oil is ready to encourage steadiness and optimum functioning in your physique.

Are you curious as to how the EC system works and its function? Right here we dive into the science behind the EC system, and talk about how with CBD oil dietary supplements you’ll be able to help its efforts to maintain you balanced.

What’s the EC System?

The EC system is a significant signaling community answerable for maintaining a big selection of our physique’s capabilities balanced and working at their greatest.

Everyone has an EC system, which works repeatedly to maintain vital capabilities like temper, sleep patterns, urge for food, reminiscence, metabolism, immune response, and extra, balanced and working optimally.

Anytime modifications within the exterior setting trigger a operate beneath the EC system’s watch to change into imbalanced, the EC system responds by triggering a collection of chemical reactions designed to carry that operate again to the place it needs to be.

As you’ll be able to think about, a effectively working EC system is essential for reaching and sustaining well being and wellness. There may be even a idea known as endocannabinoid system deficiency that means dysfunction within the human endocannabinoid system results in well being points. This idea, launched in 2004 by Dr. Ethan Russo, additionally speculates that the EC system may be supplemented and supported by consuming a category of plant derived various chemical compounds known as cannabinoids.1

All mammals depend on the EC system to maintain functioning working optimally, even your pets.

How Does the EC System Work?

Curious in regards to the function of the endocannabinoid system in your physique? Right here is a little more about how this self regulatory system capabilities. 

Your EC system is made up of three elements:

Collectively, these three mechanisms work collectively to watch a lot of your physique’s capabilities and make changes as wanted at any time when they change into imbalanced.

Let’s say, for instance, that your immune system response turns into imbalanced and begins to dysfunction. Your EC system responds by triggering the discharge of enzymes that synthesize cannabinoids, or endocannabinoids.

What do endocannabinoids do? As soon as synthesized, these body-made cannabinoids — Anandamide and 2-arachidonoylglycerol — bind to cannabinoid receptors positioned all through your physique. The EC system predominantly consists of two kinds of endocannabinoid receptors: CB1, positioned primarily within the mind and central nervous system, and CB2, most densely populated all through the peripheral nervous system.

As soon as activated by cannabinoids, these cannabinoid receptors modify the passage of proteins between cells, sending out alerts for the physique to make the changes essential to get your operate, on this case your immune system response, again to the place it needs to be.

As soon as a operate is again in steadiness, the EC system “turns off” the method by triggering the discharge of enzymes that break down cannabinoids in order that they not work together with receptors.

cannabinoid receptors and pain

cannabinoid receptors and pain


The right way to Assist the EC System

Incorporating cannabinoid merchandise like CBD oil into your each day wellness routine will help help your EC system and its efforts to maintain the physique and its capabilities balanced.

CBD oil is a botanical extract made out of high-CBD, low-THC hemp. CBD, quick for cannabidiol, is certainly one of over 100 plant-derived cannabinoids (phytocannabinoids) presently recognized in hashish vegetation. In hemp, CBD dominates the plant’s make-up.

Identical to physique synthesized endocannabinoids, plant derived cannabinoids like CBD work together along with your EC system’s cannabinoid receptors. By means of its interplay with cannabinoid receptors, CBD stimulates the EC system, encouraging the regulatory system to extra effectively maintain capabilities degree.

As you learn extra in regards to the endocannabinoid system and CBD, you’ll uncover that CBD doesn’t instantly activate the EC system’s CB1 or CB2 receptors. As a substitute, CBD interacts not directly with them and works to suppress the CB1 and CB2 activating qualities of different cannabinoids.

Most individuals do little or no to help the well being of the EC system as a result of cannabinoids haven’t been a part of the common weight loss plan for many years. Repeatedly taking CBD oil merchandise as dietary dietary supplements can increase the physique’s personal cannabinoids to help a correctly working EC system.

Whereas derived from hashish, CBD shouldn’t be intoxicating. This implies it is not going to trigger any short-term euphoric results like THC, or tetrahydrocannabinol, a cannabinoid related to marijuana.

Hemp naturally accommodates not more than zero.three p.c THC by dry weight. As such, CBD oil derived from hemp accommodates solely hint ranges of THC, far lower than the quantity wanted for intoxicating, or a “excessive.” Supporting the EC system with CBD oil has been discovered to be secure with no severe opposed unwanted effects. That is notably helpful for anybody within the pure balancing properties of cannabinoids but need to keep away from intoxicating results. Right here is extra in regards to the variations between CBD hemp oil and marijuana

As soon as extracted from hemp, CBD oil focus may be taken by itself or infused into varied kinds of merchandise, together with CBD tinctures, CBD capsules, CBD vape oil, CBD topicals and physique care merchandise, and extra. It can be refined to create concentrated merchandise like CBD isolate. There are even CBD merchandise for pets.

endocannabinoid system overview

endocannabinoid system overview


Myths Surrounding the EC System

With all of the contradictory and complicated writings on the market in regards to the EC system, it may be arduous to find out what’s fact and what’s misinformation.

There are a number of misconceptions in regards to the EC system that usually pop up in the event you search, “What’s the EC system?” Right here we tackle the 4 most typical EC system-related myths to assist make clear any confusion you have got in regards to the EC system and the way it works.

Delusion #1: The EC system emerged within the human physique due to hashish use.

Scientists did first uncover the EC system by retracing the metabolic pathway of hashish derived cannabinoids. Nevertheless, the EC system didn’t emerge within the human physique due to using hashish and absorption of its cannabinoids. The EC system was already in place, permitting cannabinoids like CBD to work together with the system and encourage its efficiency.

Delusion #2: CB1 receptors are solely within the mind and central nervous system, whereas CB2 receptors are solely within the peripheral nervous system.

Whereas it’s true that CB1 and CB2 receptors are most closely concentrated in these areas of the physique, each kinds of receptors are extra broadly distributed and located on cells all all through the physique.

Delusion #three: THC binds to CB1 receptors and CBD binds to CB2 receptors.

Like all cannabinoids, THC and CBD each work together with the EC system and its specialised cannabinoid receptors, CB1 and CB2. Nevertheless, whereas THC instantly binds with each CB1 and CB2 receptors, CBD has little affinity for the 2 receptors and doesn’t bind to both. As a substitute, it acts as an oblique antagonist and suppresses the receptors’ skills to be activated by different compounds.

Delusion #four: Cannabinoids are solely present in hashish vegetation.

Cannabinoids and cannabinoid-like substances that work together with the EC system are literally discovered in lots of vegetation. Outdoors of hemp and marijuana, cannabinoids are present in Echinacea, electrical daisy, helichrysum umbraculigerum, liverwort, black pepper, cacao, black truffles, and extra.

why do we have cannabinoid receptors

why do we have cannabinoid receptors


Extra In regards to the EC System and CBD

There have been hundreds of research executed on cannabinoids and their potential advantages. Be taught much more in regards to the EC system and the way its efforts may be supported by means of using CBD oil merchandise by visiting our CBD Oil Training web page.


  1. Russo, E.B. (2004, Feb-Apr). Scientific endocannabinoid deficiency (CECD): can this idea clarify therapeutic advantages of hashish in migraine, fibromyalgia, irritable bowel syndrome and different treatment-resistant situations? Neuro Endocrinology Letters, 25(1-2), 31-9.
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